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Bringing new hope with mRNA-targeted drugs Bringing new hope with mRNA-targeted drugs

Providing appropriate treatment for any disease Providing appropriate treatment for any disease

Veritas In Silico is unveiling the mysteries of RNA and harnessing the potential of messenger RNA (mRNA) as a drug target. Powered by our proprietary in silico technology, we have established an entirely new system for drug discovery that focuses on finding drugs against structural motifs on mRNA.
The discovery of drugs that target mRNA is a promising direction for drug development and a new paradigm for the pharmaceutical industry. It has the potential for application to any disease, including those for which conventional protein-targeted discovery has not yielded effective treatments.
Veritas In Silico’s mission is to build a society where every patient, especially those with diseases that currently have no satisfactory treatment, can look forward to a brighter future through the realization of mRNA-targeted drugs.

A pathfinder in drug discovery A pathfinder in drug discovery

With our ibVIS platform that combines informatics (i) and experimental biology (b), we at Veritas In Silico (VIS) will bring to fruition mRNA-targeted drugs.
The most distinctive feature of the ibVIS platform is its ability to maximize the existing drug discovery infrastructure — the technologies, experience, and chemical libraries — of our partner companies. We believe that the ibVIS platform will help to uncover the many hidden possibilities of mRNA as a drug target.
Armed with our platform and as pathfinders, we will guide companies willing to embark upon this new frontier of mRNA-targeted drug discovery.

The story behind our name, Veritas In Silico

Veritas In Silico

Inspired by the Latin saying in vino veritas or “in wine there is truth,” Veritas In Silico means that the truth will be revealed through computer-powered biological research.
The company name conveys our strengths, approaching the truth through deduction by using in silico technologies and verifying such truths using experimental biology approaches that enable the discovery of mRNA-targeted drugs.

Company Profile

Name Veritas In Silico Inc.
Main Office 1-11-1 Nishigotanda, Shinagawa-ku, Tokyo 141-0031 Japan
Research Facilities Basic Research Facility  Kanagawa, Japan
Applied Research Facility  Niigata, Japan
Established November 17, 2016
Employees 14
Business Description Platform business for the discovery of mRNA-targeted small molecule and antisense oligonucleotide drugs

Basic Research Facility in Kanagawa

History

November 2016

Veritas In Silico founded

The company was founded to discover mRNA-targeted small molecule and antisense oligonucleotide (ASO) drugs based on the in silico technology of RNA structural analysis, with its head office located in Shibuya, Tokyo.

2016

May–August 2017

Capital raised through Series A financing

The company raised capital in Series A financing from Mitsubishi Gas Chemical Company, Inc. (MGC) and three venture capital firms and its business has started in earnest.

2017

 

Research focuses: ASO and sgASO drug discovery

The company initially focused on discovering ASOs and small guide antisense oligonucleotides (sgASOs), which have lengths less than half of the regular ASOs.

 

July 2017

Research facility opened at NUPALS

The company opened its Applied Research Division in Niigata, at the Niigata University of Pharmacology and Applied Health Sciences (NUPALS) where Professor Masayuki Nashimoto, a leading scientist in the sgASO field, belongs.

 

 

Launch of the mRNA-targeted small molecule drug discovery

The company made a strategic decision to quickly add research capacity for mRNA-targeted small molecule drug discovery, seeing as several U.S. companies pursuing RNA-targeted small molecule drug discovery had established.

 

October 2017

Head office transferred

The company transferred its head office to its current location in Shinagawa, Tokyo.

 

March 2018

First joint research for mRNA-targeted small molecule drug discovery

The company started the first joint research with one of the domestic pharmaceutical companies to discover mRNA-targeted small molecule drugs.

2018

April 2018

Research facility opened at KBIC

The company opened its Basic Research Division for mRNA-targeted small molecule drug discovery in Shin-Kawasaki, at the Kawasaki Business Incubation Center (KBIC).

 

March-April 2019

Capital raised through Series B financing

The company raised capital in Series B financing from the existing shareholders and three additional venture capital firms, which led to the decision to focus on mRNA-targeted small molecule drug discovery officially.

2019

October 2020

Acquisition of a business model patent

The company obtained a business model patent for RNA-targeted small molecule drug discovery (Japan).

2020

December 2021

Capital raised through Series C financing

The company decided to expand the drug discovery platform business for mRNA-targeted small molecule drugs by developing or introducing new technologies.

2021

May 2023

Business cooperation with CRO

The company entered an MOU with Oncodesign Services, a well-known CRO in France, to meet the wide-ranging needs of pharmaceutical companies seeking to develop mRNA-targeted small molecule drugs.

2023

February 2024

Listed on the Growth market of the Tokyo Stock Exchange

 

2024

As of February 2024

Joint Drug Discovery Research Underway with 4 partners

The company is now conducting joint drug discovery research with Toray Industries, Inc., Shionogi Inc., RaQualia Pharma Inc. and Takeda Pharmaceutical Company Limited. to create mRNA-targeted small molecule drugs.