Medical application of small guide ASOs for tRNase ZL-utilizing efficacious (TRUE) gene silencing
RNA structural biology
ASO evaluation in animal and human iPS cells
Computational chemistry in drug design
Design research on RNA-targeting small-molecule and nucleic acid therapeutics using X-ray crystallography
Establishment of in vivo animal evaluation systems; efficacy evaluation of pharmaceuticals using these systems; and proof of concept (PoC) for therapeutic concepts using the relevant animal models.
Specializes in interventional radiology-delivering image-guided therapies that span the full continuum of cancer care, from precise diagnosis to targeted treatment and symptom palliation.